DLGAP1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
PPP3CB
Gene Ontology Biological Process
- T cell differentiation [IMP]
- T cell homeostasis [IMP]
- calcineurin-NFAT signaling cascade [ISO]
- calcium ion-dependent exocytosis [IDA]
- cellular response to drug [ISO]
- dephosphorylation [IDA]
- heart development [IMP]
- locomotion involved in locomotory behavior [IMP]
- lymphangiogenesis [IGI]
- negative regulation of T cell mediated cytotoxicity [IMP]
- positive regulation of NFAT protein import into nucleus [ISO]
- positive regulation of insulin secretion involved in cellular response to glucose stimulus [IMP, ISO]
- positive regulation of transcription from RNA polymerase II promoter [ISO]
- protein dephosphorylation [IMP, ISO]
- protein phosphorylation [IMP]
- regulation of gene expression [IMP]
- regulation of insulin secretion [ISO]
- response to cytokine [IMP]
- response to stress [IMP]
Gene Ontology Molecular Function- calcium ion binding [ISO]
- calcium-dependent protein serine/threonine phosphatase activity [ISO]
- calmodulin binding [ISO]
- calmodulin-dependent protein phosphatase activity [IMP]
- drug binding [ISO]
- enzyme binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- protein phosphatase 2B binding [ISO]
- protein serine/threonine phosphatase activity [IDA]
- calcium ion binding [ISO]
- calcium-dependent protein serine/threonine phosphatase activity [ISO]
- calmodulin binding [ISO]
- calmodulin-dependent protein phosphatase activity [IMP]
- drug binding [ISO]
- enzyme binding [ISO]
- protein binding [IPI]
- protein dimerization activity [ISO]
- protein heterodimerization activity [ISO]
- protein phosphatase 2B binding [ISO]
- protein serine/threonine phosphatase activity [IDA]
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Long-term potentiation modulates synaptic phosphorylation networks and reshapes the structure of the postsynaptic interactome.
The postsynaptic site of neurons is composed of more than 1500 proteins arranged in protein-protein interaction complexes, the composition of which is modulated by protein phosphorylation through the actions of complex signaling networks. Components of these networks function as key regulators of synaptic plasticity, in particular hippocampal long-term potentiation (LTP). The postsynaptic density (PSD) is a complex multicomponent structure that ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
DLGAP1 PPP3CB | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | 2333939 |
Curated By
- BioGRID