MYH6
Gene Ontology Biological Process
- ATP catabolic process [IDA]
- adult heart development [IMP]
- atrial cardiac muscle tissue morphogenesis [IMP]
- cardiac muscle fiber development [ISS]
- in utero embryonic development [ISS]
- muscle contraction [IDA]
- muscle filament sliding [IMP, TAS]
- myofibril assembly [ISS]
- regulation of ATPase activity [ISS]
- regulation of blood pressure [ISS]
- regulation of heart contraction [ISS]
- regulation of heart rate [IDA]
- regulation of the force of heart contraction [IDA, ISS]
- sarcomere organization [ISS]
- striated muscle contraction [IMP, ISS]
- ventricular cardiac muscle tissue morphogenesis [IMP]
- visceral muscle development [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BAG3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Myosin heavy chain is stabilized by BCL-2 interacting cell death suppressor (BIS) in skeletal muscle.
BCL-2 interacting cell death suppressor (BIS), which is ubiquitously expressed, has important roles in various cellular processes, such as apoptosis, the cellular stress response, migration and invasion and protein quality control. In particular, BIS is highly expressed in skeletal and cardiac muscles, and BIS gene mutations result in human myopathy. In this study, we show that mRNA and protein levels ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| BAG3 MYH6 | Affinity Capture-Western Affinity Capture-Western An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins. | Low | - | BioGRID | - |
Curated By
- BioGRID