TFG2
Gene Ontology Biological Process
- RNA polymerase II transcriptional preinitiation complex assembly [IC]
- promoter clearance from RNA polymerase II promoter [IC]
- transcription elongation from RNA polymerase II promoter [IDA]
- transcription initiation from RNA polymerase II promoter [IDA]
- transcriptional start site selection at RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
DST1
Gene Ontology Biological Process
- mRNA cleavage [IDA, IMP]
- maintenance of transcriptional fidelity during DNA-templated transcription elongation from RNA polymerase II promoter [IGI, IMP]
- positive regulation of RNA polymerase II transcriptional preinitiation complex assembly [IDA, IMP]
- positive regulation of transcription elongation from RNA polymerase II promoter [IDA]
- regulation of mRNA 3'-end processing [IGI, IMP]
- tRNA transcription from RNA polymerase III promoter [IMP]
- transcription antitermination [IDA]
- transcription elongation from RNA polymerase I promoter [IDA]
- transcription elongation from RNA polymerase II promoter [IDA, IMP]
- transcription from RNA polymerase III promoter [IDA]
- transcription initiation from RNA polymerase II promoter [IDA, IGI, IMP]
Gene Ontology Molecular Function
Co-purification
An interaction is inferred from the identification of two or more protein subunits in a purified protein complex, as obtained by classical biochemical fractionation or affinity purification and one or more additional fractionation steps.
Publication
A novel collection of accessory factors associated with yeast RNA polymerase II.
A relatively simple subset of general transcription factors is sufficient for transcript initiation by RNA polymerase II. However, a recently identified "holoenzyme" contains additional accessory proteins required for mediating signals from some activators (Y-J. Kim et al., 1994, Cell 77, 599-608; A. Koleske and R. Young, 1994, Nature 368, 466-469). By immobilizing RNA polymerase II and associated proteins (RAPs) from ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TFG2 DST1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -2.6151 | BioGRID | 224361 |
Curated By
- BioGRID