SWR1
Gene Ontology Biological Process
Gene Ontology Molecular Function
TAF14
Gene Ontology Biological Process
- RNA polymerase II transcriptional preinitiation complex assembly [IC]
- chromatin remodeling [IC]
- histone acetylation [IDA]
- nucleosome mobilization [IDA]
- promoter clearance from RNA polymerase II promoter [IC]
- transcription elongation from RNA polymerase II promoter [IC]
- transcription from RNA polymerase II promoter [IDA]
- transcription initiation from RNA polymerase II promoter [IDA]
- transcriptional start site selection at RNA polymerase II promoter [IC]
Gene Ontology Molecular Function- DNA translocase activity [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- core RNA polymerase II binding transcription factor activity [IDA]
- core RNA polymerase II recruiting transcription factor activity [IC]
- DNA translocase activity [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- core RNA polymerase II binding transcription factor activity [IDA]
- core RNA polymerase II recruiting transcription factor activity [IC]
Gene Ontology Cellular Component
- Ino80 complex [IDA, IPI]
- NuA3 histone acetyltransferase complex [IDA]
- NuA3a histone acetyltransferase complex [IDA]
- NuA3b histone acetyltransferase complex [IDA]
- SWI/SNF complex [IDA, IPI]
- mediator complex [IPI]
- nucleus [IDA]
- transcription factor TFIID complex [IDA]
- transcription factor TFIIF complex [IDA, IPI]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Structural analyses of the chromatin remodelling enzymes INO80-C and SWR-C.
INO80-C and SWR-C are conserved members of a subfamily of ATP-dependent chromatin remodelling enzymes that function in transcription and genome-maintenance pathways. A crucial role for these enzymes is to control chromosomal distribution of the H2A.Z histone variant. Here we use electron microscopy (EM) and two-dimensional class averaging to demonstrate that these remodelling enzymes have similar overall architectures. Each enzyme is ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| TAF14 SWR1 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1802 | BioGRID | 2191481 |
Curated By
- BioGRID