SSC1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
BUD2
Gene Ontology Biological Process
- axial cellular bud site selection [IMP]
- bipolar cellular bud site selection [IMP]
- establishment or maintenance of cell polarity [IMP]
- filamentous growth [IMP]
- invasive filamentous growth [IMP]
- mitotic spindle orientation checkpoint [IMP]
- negative regulation of Ras protein signal transduction [IBA]
- positive regulation of Ras GTPase activity [IBA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Mitochondrial heat shock protein (Hsp) 70 and Hsp10 cooperate in the formation of Hsp60 complexes.
Mitochondrial Hsp70 (mtHsp70) mediates essential functions for mitochondrial biogenesis, like import and folding of proteins. In these processes, the chaperone cooperates with cochaperones, the presequence translocase, and other chaperone systems. The chaperonin Hsp60, together with its cofactor Hsp10, catalyzes folding of a subset of mtHsp70 client proteins. Hsp60 forms heptameric ring structures that provide a cavity for protein folding. How ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SSC1 BUD2 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.1946 | BioGRID | 1994330 |
Curated By
- BioGRID