BAIT

WRKY40

ATWRKY40, F23A5.19, F23A5_19, WRKY DNA-binding protein 40, AT1G80840
putative WRKY transcription factor 40
Arabidopsis thaliana (Columbia)
PREY

WRKY60

ATWRKY60, F27C12.8, F27C12_8, WRKY DNA-binding protein 60, AT2G25000
putative WRKY transcription factor 60
Arabidopsis thaliana (Columbia)

Phenotypic Enhancement

A genetic interaction is inferred when mutation or overexpression of one gene results in enhancement of any phenotype (other than lethality/growth defect) associated with mutation or over expression of another gene.

Publication

Regulation of oncogene expression in T-DNA-transformed host plant cells.

Zhang Y, Lee CW, Wehner N, Imdahl F, Svetlana V, Weiste C, Droege-Laser W, Deeken R

Virulent Agrobacterium tumefaciens strains integrate their T-DNA into the plant genome where the encoded agrobacterial oncogenes are expressed and cause crown gall disease. Essential for crown gall development are IaaH (indole-3-acetamide hydrolase), IaaM (tryptophan monooxygenase) and Ipt (isopentenyl transferase), which encode enzymes for the biosynthesis of auxin (IaaH, IaaM) and cytokinin (Ipt). Although these oncogenes are well studied as the ... [more]

PLoS Pathog. Jan. 01, 2015; 11(1);e1004620 [Pubmed: 25615824]

Throughput

  • Low Throughput

Additional Notes

  • triple wrky18/60/40 mutant plants develops smaller crown galls than wild-type

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
WRKY40 WRKY60
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

High-BioGRID
-
WRKY40 WRKY60
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-
WRKY60 WRKY40
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID