RPN10
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
SPT15
Gene Ontology Biological Process
Gene Ontology Molecular Function- DNA binding, bending [IDA]
- RNA polymerase I transcription factor binding [IDA, IPI]
- RNA polymerase I transcription factor recruiting transcription factor activity [IDA, IPI]
- RNA polymerase II activating transcription factor binding [IDA, IPI]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- RNA polymerase III regulatory region DNA binding [IDA]
- TFIIIB-type transcription factor activity [IC]
- chromatin binding [IDA]
- sequence-specific DNA binding [IDA]
- DNA binding, bending [IDA]
- RNA polymerase I transcription factor binding [IDA, IPI]
- RNA polymerase I transcription factor recruiting transcription factor activity [IDA, IPI]
- RNA polymerase II activating transcription factor binding [IDA, IPI]
- RNA polymerase II core promoter sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter sequence-specific DNA binding transcription factor activity involved in preinitiation complex assembly [IC]
- RNA polymerase III regulatory region DNA binding [IDA]
- TFIIIB-type transcription factor activity [IC]
- chromatin binding [IDA]
- sequence-specific DNA binding [IDA]
Gene Ontology Cellular Component
Co-fractionation
Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.
Publication
Son1p is a component of the 26S proteasome of the yeast Saccharomyces cerevisiae.
A son1 mutant was isolated as a mutant showing synthetic lethality with nin1-1 which is defective in the p31 component of the regulatory subunit of the yeast 26S proteasome. son1delta showed a synthetic effect with sen3delta and sun1delta, both components of the 26S proteasome, and with cdc28-1N. The 26S proteasome was partially purified from the wild type yeast. The FPLC ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| SPT15 RPN10 | Negative Genetic Negative Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a more severe fitness defect or lethality under a given condition. This term is reserved for high or low throughput studies with scores. | High | -0.12 | BioGRID | 1977079 | |
| RPN10 SPT15 | Positive Genetic Positive Genetic Mutations/deletions in separate genes, each of which alone causes a minimal phenotype, but when combined in the same cell results in a less severe fitness defect than expected under a given condition. This term is reserved for high or low throughput studies with scores. | High | 0.2952 | BioGRID | 1896591 |
Curated By
- BioGRID