SCS2
Gene Ontology Biological Process
- chromatin silencing at telomere [IGI, IMP]
- endoplasmic reticulum inheritance [IGI, IMP]
- endoplasmic reticulum membrane organization [IGI]
- endoplasmic reticulum polarization [IDA]
- negative regulation of transcription factor import into nucleus [IMP, IPI]
- phospholipid biosynthetic process [IGI, IMP]
- regulation of intracellular lipid transport [IMP]
- regulation of phosphatidylinositol dephosphorylation [IGI]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
INO1
Gene Ontology Biological Process
Gene Ontology Molecular Function
Dosage Rescue
A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.
Publication
The Saccharomyces cerevisiae SCS2 gene product, a homolog of a synaptobrevin-associated protein, is an integral membrane protein of the endoplasmic reticulum and is required for inositol metabolism.
The Saccharomyces cerevisiae SCS2 gene has been cloned as a suppressor of inositol auxotrophy of CSE1 and hac1/ire15 mutants (J. Nikawa, A. Murakami, E. Esumi, and K. Hosaka, J. Biochem. 118:39-45, 1995) and has homology with a synaptobrevin/VAMP-associated protein, VAP-33, cloned from Aplysia californica (P. A. Skehel, K. C. Martin, E. R. Kandel, and D. Bartsch, Science 269:1580-1583, 1995). In ... [more]
Throughput
- Low Throughput
Ontology Terms
- phenotype: auxotrophy (APO:0000097)
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
SCS2 INO1 | Dosage Rescue Dosage Rescue A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene. | Low | - | BioGRID | 518728 |
Curated By
- BioGRID