BAIT
ABF1
BAF1, OBF1, REB2, SBF1, DNA-binding protein ABF1, L000000159, YKL112W
DNA binding protein with possible chromatin-reorganizing activity; involved in transcriptional activation, gene silencing, and DNA replication and repair
GO Process (6)
GO Function (5)
GO Component (2)
Gene Ontology Biological Process
- DNA-dependent DNA replication [IDA]
- chromatin remodeling [IDA, IGI]
- chromatin silencing at silent mating-type cassette [IMP]
- global genome nucleotide-excision repair [IDA, IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IMP]
Gene Ontology Molecular Function- DNA replication origin binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding, bending [IDA]
- DNA replication origin binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding [IDA]
- RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription [IDA]
- sequence-specific DNA binding [IDA]
- sequence-specific DNA binding, bending [IDA]
Gene Ontology Cellular Component
Saccharomyces cerevisiae (S288c)
PREY
TRP1
phosphoribosylanthranilate isomerase TRP1, L000002352, YDR007W
Phosphoribosylanthranilate isomerase; catalyzes the third step in tryptophan biosynthesis; in 2004, the sequence of TRP1 from strain S228C was updated by changing the previously annotated internal STOP (TAA) to serine (TCA)
GO Process (1)
GO Function (1)
GO Component (1)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Saccharomyces cerevisiae (S288c)
Dosage Rescue
A genetic interaction is inferred when over expression or increased dosage of one gene rescues the lethality or growth defect of a strain that is mutated or deleted for another gene.
Publication
Molecular cloning and characterization of the Saccharomyces cerevisiae SAB1 gene that suppresses a temperature-sensitive phenotype of the ARS-binding factor 1 mutant.
A high-copy number suppressor gene of the yeast temperature-sensitive lethal abf1 mutant was isolated and named SAB1 (suppressor of ABF1). Chromoblot hybridization and grid-filter hybridization analyses showed that the SAB1 gene was located on chromosome IV. Deletion analyses of the SAB1 plasmid revealed that the suppressor activity was contained in a 1.1 kb DNA region. The nucleotide sequence of the ... [more]
Mol. Cells Aug. 31, 1997; 7(4);532-6 [Pubmed: 9339899]
Throughput
- Low Throughput
Ontology Terms
- temperature sensitive growth (APO:0000092)
Curated By
- BioGRID