BAIT
BIM1
YEB1, microtubule-binding protein BIM1, EB1, L000003272, YER016W
Microtubule plus end-tracking protein; together with Kar9p makes up the cortical microtubule capture site and delays the exit from mitosis when the spindle is oriented abnormally
GO Process (7)
GO Function (3)
GO Component (6)
Gene Ontology Biological Process
- microtubule depolymerization [IMP]
- microtubule nucleation [IPI]
- mitotic sister chromatid cohesion [IGI, IMP]
- mitotic spindle assembly checkpoint [TAS]
- negative regulation of microtubule depolymerization [IMP]
- nuclear migration along microtubule [IMP]
- positive regulation of microtubule polymerization [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Saccharomyces cerevisiae (S288c)
PREY
BUD25
YER014C-A
Protein involved in bud-site selection; diploid mutants display a random budding pattern instead of the wild-type bipolar pattern
GO Process (1)
GO Function (0)
GO Component (0)
Gene Ontology Biological Process
Saccharomyces cerevisiae (S288c)
Synthetic Lethality
A genetic interaction is inferred when mutations or deletions in separate genes, each of which alone causes a minimal phenotype, result in lethality when combined in the same cell under a given condition.
Publication
A robust toolkit for functional profiling of the yeast genome.
Study of mutant phenotypes is a fundamental method for understanding gene function. The construction of a near-complete collection of yeast knockouts (YKO) and the unique molecular barcodes (or TAGs) that identify each strain has enabled quantitative functional profiling of Saccharomyces cerevisiae. By using these TAGs and the SGA reporter, MFA1pr-HIS3, which facilitates conversion of heterozygous diploid YKO strains into haploid ... [more]
Mol. Cell Nov. 05, 2004; 16(3);487-96 [Pubmed: 15525520]
Throughput
- High Throughput
Ontology Terms
- phenotype: inviable (APO:0000112)
Curated By
- BioGRID