PREY

DLG3

MRX, MRX90, NEDLG, PPP1R82, SAP102, XLMR, RP11-291O7.3
discs, large homolog 3 (Drosophila)
GO Process (4)
GO Function (2)
GO Component (2)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Selective interaction of megalin with postsynaptic density-95 (PSD-95)-like membrane-associated guanylate kinase (MAGUK) proteins.

Larsson M, Hjaelm G, Sakwe AM, Engstroem A, Hoeglund AS, Larsson E, Robinson RC, Sundberg C, Rask L

Megalin is an integral membrane receptor belonging to the low-density lipoprotein receptor family. In addition to its role as an endocytotic receptor, megalin has also been proposed to have signalling functions. Using interaction cloning in yeast, we identified the membrane-associated guanylate kinase family member postsynaptic density-95 (PSD-95) as an interaction partner for megalin. PSD-95 and a truncated version of megalin ... [more]

Biochem. J. Jul. 15, 2003; 373(0);381-91 [Pubmed: 12713445]

Throughput

  • Low Throughput

Curated By

  • BioGRID