nuclear RNA export factor 3
GO Process (1)
GO Function (1)
GO Component (4)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens


Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.


Two closely related human nuclear export factors utilize entirely distinct export pathways.

Yang J, Bogerd HP, Wang PJ, Page DC, Cullen BR

Nuclear mRNA export mediated by the human protein TAP requires a carboxy-terminal domain that directly interacts with components of the nuclear pore complex. Here we demonstrate that NXF3, a human RNA binding protein related to TAP, lacks this domain yet retains the ability to export tethered RNA transcripts and to shuttle between the nucleus and the cytoplasm. NXF3 contains a ... [more]

Mol. Cell Aug. 01, 2001; 8(2);397-406 [Pubmed: 11545741]


  • Low Throughput

Curated By

  • BioGRID