BAIT

PQBP1

MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS, JM26
polyglutamine binding protein 1
GO Process (3)
GO Function (3)
GO Component (4)
Homo sapiens
PREY

TXNL4A

DIB1, DIM1, HsT161, SNRNP15, TXNL4, U5-15kD
thioredoxin-like 4A
GO Process (5)
GO Function (1)
GO Component (2)
Homo sapiens

Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Evidence that dim1 associates with proteins involved in pre-mRNA splicing, and delineation of residues essential for dim1 interactions with hnRNP F and Npw38/PQBP-1.

Zhang Y, Lindblom T, Chang A, Sudol M, Sluder AE, Golemis EA

The small evolutionarily conserved protein Dim1p/hDim1/Dib1p/DML-1 was initially defined as a factor essential for progression through the G2/M transition, and shown to be required to maintain the steady state level of a component of the fission yeast anaphase promoting complex/cyclosome. More recently, Dib1p has been defined as a component of the U4/U6.U5 tri-snRNP, required for pre-mRNA splicing. To investigate the ... [more]

Gene Oct. 17, 2000; 257(1);33-43 [Pubmed: 11054566]

Throughput

  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
PQBP1 TXNL4A
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-
TXNL4A PQBP1
Two-hybrid
Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Low-BioGRID
-

Curated By

  • BioGRID