AIP-3, AIP3, BAIAP1, BAP-1, BAP1, MAGI-1, Magi1d, TNRC19, WWP3, RP11-88H12.2
membrane associated guanylate kinase, WW and PDZ domain containing 1
GO Process (4)
GO Function (3)
GO Component (5)
Homo sapiens


Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.


The membrane-associated guanylate kinase protein MAGI-1 binds megalin and is present in glomerular podocytes.

Patrie KM, Drescher AJ, Goyal M, Wiggins RC, Margolis B

The transmembrane endocytic receptor glycoprotein 330/megalin (hereafter referred to as megalin) is localized to the apical membrane domain of epithelial cells, where it is involved in the uptake of proteins from extracellular sources. The cytoplasmic domain of megalin contains amino acid motifs that have the potential to bind to other proteins, which may influence its localization or function. The yeast ... [more]

J. Am. Soc. Nephrol. Apr. 01, 2001; 12(4);667-77 [Pubmed: 11274227]


  • Low Throughput

Related interactions

InteractionExperimental Evidence CodeDatasetThroughputScoreCurated ByNotes
Reconstituted Complex
Reconstituted Complex

An interaction is detected between purified proteins in vitro.


Curated By

  • BioGRID