Two-hybrid

Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.

Publication

Targeting of p0071 to desmosomes and adherens junctions is mediated by different protein domains.

Hatzfeld M, Green KJ, Sauter H

p0071, a member of the armadillo protein family, is most closely related to p120(ctn) and the plakophilins 1-3. Whereas plakophilins are desmosomal plaque proteins, p120(ctn) localizes to adherens junctions and interacts with classical cadherins. In contrast, p0071 has been described as a protein with dual localization in adherens junctions and desmosomes depending on the cell type examined. Here we have ... [more]

J. Cell. Sci. Apr. 01, 2003; 116(0);1219-33 [Pubmed: 12615965]

Throughput

  • Low Throughput

Curated By

  • BioGRID