MED11
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
MED6
Gene Ontology Biological Process
- defense response to Gram-negative bacterium [IMP]
- lateral inhibition [IMP]
- negative regulation of innate immune response [IMP]
- negative regulation of neuroblast proliferation [IMP]
- regulation of transcription from RNA polymerase II promoter [IDA]
- transcription from RNA polymerase II promoter [IMP, ISS]
- transcription initiation from RNA polymerase II promoter [ISS]
Gene Ontology Molecular Function
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Novel Mediator proteins of the small Mediator complex in Drosophila SL2 cells.
The Mediator complex is generally required for transcriptional regulation in species ranging from yeast to human. Throughout evolution, the functional diversity of the Mediator complex has been enhanced to meet the increasing requirements for sophisticated gene regulation. It is likely that greater structural complexity is thus required to accomplish these new, complex regulatory functions. In this study, we took systematic ... [more]
Throughput
- Low Throughput
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| MED6 MED11 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID