BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MYH10
MCH-B, NMMHC-B, SMemb
myosin, heavy chain 10, non-muscle
GO Process (28)
GO Function (6)
GO Component (21)
Gene Ontology Biological Process
- ATP catabolic process [ISO]
- actin cytoskeleton organization [ISO]
- actin filament-based movement [ISO]
- actomyosin structure organization [ISO]
- adult heart development [ISO]
- axon guidance [ISO]
- axonogenesis [ISO]
- brain development [ISO]
- cardiac myofibril assembly [ISO]
- cell proliferation [ISO]
- cellular component movement [NAS]
- cerebellar Purkinje cell layer development [ISO]
- exocytosis [ISO]
- fourth ventricle development [ISO]
- in utero embryonic development [ISO]
- lateral ventricle development [ISO]
- mitotic cytokinesis [ISO]
- myofibril assembly [ISO]
- neuromuscular process controlling balance [ISO]
- neuron migration [ISO]
- neuron projection development [ISO]
- nuclear migration [ISO]
- plasma membrane repair [ISO]
- regulation of cell shape [ISO]
- retina development in camera-type eye [ISO]
- substrate-dependent cell migration, cell extension [ISO]
- third ventricle development [ISO]
- ventricular cardiac muscle cell development [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISO]
- actomyosin [ISO]
- axon [ISO]
- cell cortex [ISO]
- cleavage furrow [ISO]
- cytoplasm [ISO]
- dendritic spine [ISO]
- extracellular vesicular exosome [ISO]
- growth cone [ISO]
- midbody [ISO]
- mitochondrion [ISO]
- myosin II complex [ISO]
- myosin II filament [ISO]
- myosin complex [ISO]
- neuromuscular junction [ISO]
- neuron projection [ISO]
- neuronal cell body [ISO]
- nucleus [ISO]
- plasma membrane [ISO]
- spindle [ISO]
- stress fiber [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID