BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MYO5A
D, Dop, Myh12
myosin VA
GO Process (29)
GO Function (14)
GO Component (29)
Gene Ontology Biological Process
- actin filament-based movement [IDA, ISO]
- cellular response to insulin stimulus [ISO, ISS]
- developmental pigmentation [ISO]
- endoplasmic reticulum localization [ISO]
- exocytosis [ISO]
- insulin secretion [ISO]
- locomotion involved in locomotory behavior [ISO]
- long-chain fatty acid biosynthetic process [ISO]
- melanin biosynthetic process [ISO]
- melanin metabolic process [ISO]
- melanocyte differentiation [ISO]
- melanosome localization [ISO]
- melanosome transport [ISO]
- metabolic process [IDA, IMP]
- myelination [ISO]
- neuromuscular process controlling balance [ISO]
- odontogenesis [ISO]
- pigmentation [IMP, ISO]
- post-Golgi vesicle-mediated transport [ISO]
- protein localization to plasma membrane [ISO, ISS]
- regulation of Golgi organization [ISO]
- regulation of exocytosis [IMP]
- regulation of inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity [ISO]
- secretory granule localization [IDA, IMP, ISO]
- synapse organization [ISO]
- synaptic transmission [ISO]
- vesicle transport along actin filament [IMP, ISO]
- vesicle-mediated transport [ISO, ISS]
- visual perception [ISO]
Gene Ontology Molecular Function- ATP binding [IDA]
- ATP-dependent protein binding [IPI]
- Rab GTPase binding [ISO]
- SNARE binding [IPI]
- actin binding [ISO]
- calcium ion binding [ISO]
- calcium-dependent protein binding [IPI]
- calmodulin binding [ISO]
- microfilament motor activity [IDA, ISO]
- motor activity [IMP, ISO]
- poly(A) RNA binding [ISO]
- protein dimerization activity [IMP]
- protein heterodimerization activity [IDA]
- syntaxin-1 binding [IPI]
- ATP binding [IDA]
- ATP-dependent protein binding [IPI]
- Rab GTPase binding [ISO]
- SNARE binding [IPI]
- actin binding [ISO]
- calcium ion binding [ISO]
- calcium-dependent protein binding [IPI]
- calmodulin binding [ISO]
- microfilament motor activity [IDA, ISO]
- motor activity [IMP, ISO]
- poly(A) RNA binding [ISO]
- protein dimerization activity [IMP]
- protein heterodimerization activity [IDA]
- syntaxin-1 binding [IPI]
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- actin filament [ISO]
- actomyosin [ISO]
- actomyosin, myosin complex part [IDA]
- axon [IDA]
- cell [ISO]
- cytoplasm [IDA, ISO]
- cytosol [ISO]
- early endosome [ISO]
- endoplasmic reticulum [ISO]
- extracellular vesicular exosome [ISO]
- filopodium tip [ISO]
- insulin-responsive compartment [ISO, ISS]
- intermediate filament [ISO]
- late endosome [ISO]
- lysosome [ISO]
- melanosome [ISO]
- membrane [ISO]
- microtubule plus-end [ISO]
- myosin complex [ISO]
- neuron projection [IDA]
- neuronal cell body [IDA, ISO]
- peroxisome [ISO]
- photoreceptor outer segment [ISO]
- recycling endosome [ISO]
- ruffle [ISO]
- secretory granule [IDA, ISO, TAS]
- synaptic vesicle [IDA]
- vesicle [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID