BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
MYH9
myosin, heavy chain 9, non-muscle
GO Process (14)
GO Function (9)
GO Component (15)
Gene Ontology Biological Process
- ATP catabolic process [ISS]
- actin cytoskeleton reorganization [ISS]
- actin filament-based movement [ISS]
- angiogenesis [ISS]
- blood vessel endothelial cell migration [ISS]
- membrane protein ectodomain proteolysis [ISS]
- monocyte differentiation [ISS]
- platelet formation [ISS]
- positive regulation of calcium ion transport into cytosol [IMP]
- positive regulation of endocytosis [IMP]
- positive regulation of phagocytosis [IMP]
- protein transport [ISS]
- regulation of cell shape [ISS]
- sodium ion transmembrane transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- actin cytoskeleton [ISS]
- actomyosin contractile ring [ISS]
- cell leading edge [ISS]
- cleavage furrow [ISS]
- cytoplasm [IDA, ISS]
- cytosol [ISS]
- endosome [IDA]
- integrin complex [ISS]
- lateral plasma membrane [IDA]
- nucleus [ISS]
- phagocytic vesicle [IDA]
- plasma membrane [ISS]
- protein complex [IDA, ISS]
- ruffle [ISS]
- stress fiber [ISS]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID