BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
DNM1L
DLP1, Dnml1, Drp1
dynamin 1-like
GO Process (19)
GO Function (5)
GO Component (11)
Gene Ontology Biological Process
- GTP catabolic process [ISO, ISS]
- dynamin polymerization involved in mitochondrial fission [ISO, ISS]
- membrane fission involved in mitochondrial fission [ISO]
- membrane fusion [ISO]
- mitochondrial fission [ISO, ISS]
- mitochondrial fragmentation involved in apoptotic process [ISO]
- mitochondrion morphogenesis [ISO]
- necroptotic process [ISO, ISS]
- peroxisome fission [ISO, ISS]
- positive regulation of apoptotic process [ISO]
- positive regulation of intrinsic apoptotic signaling pathway [ISO]
- positive regulation of protein secretion [ISO]
- positive regulation of release of cytochrome c from mitochondria [ISO]
- protein homotetramerization [ISO]
- protein localization to mitochondrion [ISO]
- regulation of mitochondrion organization [ISO]
- regulation of peroxisome organization [ISO]
- regulation of protein oligomerization [ISO]
- release of cytochrome c from mitochondria [ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID