BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
CAR4
Ca4
carbonic anhydrase 4
GO Process (4)
GO Function (1)
GO Component (18)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [ISO]
- anchored component of external side of plasma membrane [ISO]
- anchored component of plasma membrane [ISO]
- apical plasma membrane [IDA, ISO]
- basolateral plasma membrane [ISO]
- brush border membrane [ISO]
- cell surface [ISO]
- endoplasmic reticulum-Golgi intermediate compartment [ISO]
- extracellular vesicular exosome [ISO]
- membrane [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- rough endoplasmic reticulum [ISO]
- sarcolemma [IDA]
- sarcoplasmic reticulum [IDA]
- secretory granule membrane [ISO]
- trans-Golgi network [ISO]
- transport vesicle membrane [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID