BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
PURB
pur-beta
purine rich element binding protein B
GO Process (3)
GO Function (12)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function- RNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [ISO]
- double-stranded DNA binding [ISO]
- mRNA binding [ISO, ISS]
- poly(A) RNA binding [ISO]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA, ISO, ISS]
- transcription factor binding [ISO, ISS]
- translation repressor activity, nucleic acid binding [IDA]
- RNA binding [ISO]
- RNA polymerase II regulatory region sequence-specific DNA binding [ISO]
- RNA polymerase II transcription regulatory region sequence-specific DNA binding transcription factor activity involved in negative regulation of transcription [ISO]
- SMAD binding [ISO]
- double-stranded DNA binding [ISO]
- mRNA binding [ISO, ISS]
- poly(A) RNA binding [ISO]
- purine-rich negative regulatory element binding [IDA]
- sequence-specific DNA binding transcription factor activity [ISO]
- single-stranded DNA binding [IDA, ISO, ISS]
- transcription factor binding [ISO, ISS]
- translation repressor activity, nucleic acid binding [IDA]
Gene Ontology Cellular Component
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID