BAIT
DAO
Dao1
D-amino-acid oxidase
GO Process (6)
GO Function (5)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Rattus norvegicus
PREY
STX7
syntaxin 7
GO Process (11)
GO Function (6)
GO Component (19)
Gene Ontology Biological Process
- endosome to lysosome transport [IDA]
- intracellular protein transport [IBA]
- organelle assembly [ISO]
- organelle localization [ISO]
- positive regulation of T cell mediated cytotoxicity [ISO]
- positive regulation of receptor localization to synapse [ISO]
- regulation of protein localization to plasma membrane [ISO]
- synaptic vesicle exocytosis [TAS]
- vesicle docking [IBA]
- vesicle fusion [IDA]
- vesicle-mediated transport [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- SNARE complex [IDA]
- azurophil granule [ISO]
- early endosome [ISO]
- endocytic vesicle [ISO]
- endosome [IDA, ISO]
- extracellular vesicular exosome [ISO]
- immunological synapse [ISO]
- integral component of membrane [IBA]
- intracellular membrane-bounded organelle [ISO]
- late endosome [ISO]
- late endosome membrane [IDA]
- lysosomal membrane [IDA, ISO]
- lysosome [ISO]
- perinuclear region of cytoplasm [ISO]
- plasma membrane [ISO]
- recycling endosome [ISO]
- terminal bouton [IDA]
- tertiary granule [ISO]
- vesicle [ISO]
Rattus norvegicus
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
D-amino acid oxidase activity is inhibited by an interaction with bassoon protein at the presynaptic active zone.
Schizophrenia is a highly heritable neuropsychiatric disorder affecting ∼1% of the world's population. Linkage and association studies have identified multiple candidate schizophrenia susceptibility genes whose functions converge on the glutamatergic neurotransmitter system. One such susceptibility gene encoding D-amino acid oxidase (DAO), an enzyme that metabolizes the NMDA receptor (NMDAR) co-agonist D-serine, has the potential to modulate NMDAR function in the ... [more]
J. Biol. Chem. Aug. 19, 2011; 286(33);28867-75 [Pubmed: 21700703]
Throughput
- Low Throughput
Curated By
- BioGRID