BAIT
SPTBN1
ELF, HEL102, SPTB2, betaSpII
spectrin, beta, non-erythrocytic 1
GO Process (6)
GO Function (4)
GO Component (6)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Homo sapiens
PREY
THAP3
THAP domain containing, apoptosis associated protein 3
GO Process (0)
GO Function (1)
GO Component (0)
Gene Ontology Molecular Function
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Non-erythroid beta spectrin interacting proteins and their effects on spectrin tetramerization.
With yeast two-hybrid methods, we used a C-terminal fragment (residues 1697-2145) of non-erythroid beta spectrin (βII-C), including the region involved in the association with alpha spectrin to form tetramers, as the bait to screen a human brain cDNA library to identify proteins interacting with βII-C. We applied stringent selection steps to eliminate false positives and identified 17 proteins that interacted ... [more]
Cell. Mol. Biol. Lett. Dec. 01, 2011; 16(4);595-609 [Pubmed: 21866423]
Throughput
- Low Throughput
Curated By
- BioGRID