BAIT
TMA108
TAE3, RBF108, YIL137C
Ribosome-associated protein that is involved in ribosome biogenesis; putative metalloprotease
GO Process (1)
GO Function (0)
GO Component (2)
Saccharomyces cerevisiae (S288c)
PREY
SNR18
C/D box small nucleolar RNA (snoRNA); commonly referred to as U18; guides 2'-O-methylation of large subunit (LSU) rRNA at positions A649 and C650
GO Process (0)
GO Function (0)
GO Component (0)
Saccharomyces cerevisiae (S288c)
Affinity Capture-RNA
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and associated RNA species identified by Northern blot, RT-PCR, affinity labeling, sequencing, or microarray analysis.
Publication
Tma108, a putative M1 aminopeptidase, is a specific nascent chain-associated protein in Saccharomyces cerevisiae.
The discovery of novel specific ribosome-associated factors challenges the assumption that translation relies on standardized molecular machinery. In this work, we demonstrate that Tma108, an uncharacterized translation machinery-associated factor in yeast, defines a subpopulation of cellular ribosomes specifically involved in the translation of less than 200 mRNAs encoding proteins with ATP or Zinc binding domains. Using ribonucleoparticle dissociation experiments we ... [more]
Nucleic Acids Res. Oct. 14, 2016; 44(18);8826-8841 [Pubmed: 27580715]
Throughput
- Low Throughput
Curated By
- BioGRID