BAIT

RNF138

HSD-4, NARF, STRIN, hNARF, HSD4
ring finger protein 138, E3 ubiquitin protein ligase
UPS Project
GO Process (0)
GO Function (1)
GO Component (1)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens
PREY

LYAR

ZC2HC2, ZLYAR, PNAS-5
Ly1 antibody reactive
GO Process (0)
GO Function (2)
GO Component (2)

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Ubiquitylation of Rad51d Mediated by E3 Ligase Rnf138 Promotes the Homologous Recombination Repair Pathway.

Han D, Liang J, Lu Y, Xu L, Miao S, Lu LY, Song W, Wang L

Ubiquitylation has an important role as a signal transducer that regulates protein function, subcellular localization, or stability during the DNA damage response. In this study, we show that Ring domain E3 ubiquitin ligases RNF138 is recruited to DNA damage site quickly. And the recruitment is mediated through its Zinc finger domains. We further confirm that RNF138 is phosphorylated by ATM ... [more]

PLoS ONE May. 20, 2016; 11(5);e0155476 [Pubmed: 27195665]

Throughput

  • Low Throughput

Curated By

  • BioGRID