BAIT

LNX1

Lnx
ligand of numb-protein X 1
Mus musculus
PREY

CTTNBP2

3010022N24Rik, 4732477G22Rik, 6430526E05, 9130022E09Rik, AU040881, Cortbp2, ORF4, mKIAA1758
cortactin binding protein 2
GO Process (1)
GO Function (2)
GO Component (2)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

Lenihan JA, Saha O, Heimer-McGinn V, Cryan JF, Feng G, Young PW

NUMB is a key regulator of neurogenesis and neuronal differentiation that can be ubiquitinated and targeted for proteasomal degradation by ligand of numb protein-X (LNX) family E3 ubiquitin ligases. However, our understanding of LNX protein function in vivo is very limited. To examine the role of LNX proteins in regulating NUMB function in vivo, we generated mice lacking both LNX1 ... [more]

Mol. Neurobiol. Nov. 26, 2016; 0(); [Pubmed: 27889896]

Throughput

  • High Throughput

Curated By

  • BioGRID