BAIT

LNX2

9630046H24, AW209022
ligand of numb-protein X 2
GO Process (1)
GO Function (2)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Mus musculus
PREY

SLC4A4

AI835705, NBC, NBC1
solute carrier family 4 (anion exchanger), member 4
Mus musculus

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.

Lenihan JA, Saha O, Heimer-McGinn V, Cryan JF, Feng G, Young PW

NUMB is a key regulator of neurogenesis and neuronal differentiation that can be ubiquitinated and targeted for proteasomal degradation by ligand of numb protein-X (LNX) family E3 ubiquitin ligases. However, our understanding of LNX protein function in vivo is very limited. To examine the role of LNX proteins in regulating NUMB function in vivo, we generated mice lacking both LNX1 ... [more]

Mol. Neurobiol. Nov. 26, 2016; 0(); [Pubmed: 27889896]

Throughput

  • High Throughput

Curated By

  • BioGRID