BAIT
TSC22D2
TILZ4a, TILZ4b, TILZ4c
TSC22 domain family, member 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
ATP1B1
ATP1B
ATPase, Na+/K+ transporting, beta 1 polypeptide
GO Process (25)
GO Function (5)
GO Component (6)
Gene Ontology Biological Process
- blood coagulation [TAS]
- cardiac muscle contraction [ISS]
- cell communication by electrical coupling involved in cardiac conduction [TAS]
- cellular calcium ion homeostasis [ISS]
- cellular potassium ion homeostasis [IDA]
- cellular sodium ion homeostasis [IDA]
- ion transmembrane transport [TAS]
- leukocyte migration [TAS]
- membrane repolarization [IDA]
- membrane repolarization during cardiac muscle cell action potential [IC]
- positive regulation of ATP catabolic process [IDA]
- positive regulation of ATPase activity [IDA]
- positive regulation of calcium:sodium antiporter activity [ISS]
- positive regulation of potassium ion import [IDA]
- positive regulation of potassium ion transmembrane transporter activity [IDA]
- positive regulation of sodium ion export from cell [IDA]
- potassium ion import [IDA]
- protein localization to plasma membrane [IDA]
- protein stabilization [IDA, ISS]
- protein transport into plasma membrane raft [TAS]
- regulation of cardiac muscle contraction by calcium ion signaling [ISS]
- regulation of gene expression [ISS]
- relaxation of cardiac muscle [ISS]
- sodium ion export from cell [IDA]
- transmembrane transport [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2.
Transforming growth factor β-stimulated clone 22 domain family, member 2 (TSC22D2), a member of the TSC22D family, has been implicated as a tumor-associated gene, but its function remains unknown. To further explore its biological role, yeast two-hybrid screening combined with multiple bioinformatics tools was used to identify 44 potential interacting partners of the TSC22D2 protein that were mainly involved in ... [more]
Tumour Biol. Sep. 01, 2016; 37(9);12503-12512 [Pubmed: 27337956]
Throughput
- Low Throughput
Curated By
- BioGRID