BAIT
TSC22D2
TILZ4a, TILZ4b, TILZ4c
TSC22 domain family, member 2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens
PREY
EPCAM
DIAR5, EGP-2, EGP314, EGP40, ESA, HNPCC8, KS1/4, KSA, M4S1, MIC18, MK-1, TACSTD1, TROP1
epithelial cell adhesion molecule
GO Process (6)
GO Function (2)
GO Component (6)
Gene Ontology Biological Process
- negative regulation of cell-cell adhesion mediated by cadherin [IDA]
- positive regulation of cell proliferation [IDA]
- positive regulation of stem cell proliferation [IMP]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- signal transduction involved in regulation of gene expression [IMP]
- stem cell differentiation [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Two-hybrid
Bait protein expressed as a DNA binding domain (DBD) fusion and prey expressed as a transcriptional activation domain (TAD) fusion and interaction measured by reporter gene activation.
Publication
Yeast two-hybrid screening identified WDR77 as a novel interacting partner of TSC22D2.
Transforming growth factor β-stimulated clone 22 domain family, member 2 (TSC22D2), a member of the TSC22D family, has been implicated as a tumor-associated gene, but its function remains unknown. To further explore its biological role, yeast two-hybrid screening combined with multiple bioinformatics tools was used to identify 44 potential interacting partners of the TSC22D2 protein that were mainly involved in ... [more]
Tumour Biol. Sep. 01, 2016; 37(9);12503-12512 [Pubmed: 27337956]
Throughput
- Low Throughput
Curated By
- BioGRID