BAIT

WDR4

TRM82, TRMT82
WD repeat domain 4
GO Process (1)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Cellular Component

Homo sapiens
PREY

HIST1H2BB

H2B.1, H2B/f, H2BFF
histone cluster 1, H2bb
GO Process (2)
GO Function (2)
GO Component (3)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Wuho Is a New Member in Maintaining Genome Stability through its Interaction with Flap Endonuclease 1.

Cheng IC, Chen BC, Shuai HH, Chien FC, Chen P, Hsieh TS

Replication forks are vulnerable to wayward nuclease activities. We report here our discovery of a new member in guarding genome stability at replication forks. We previously isolated a Drosophila mutation, wuho (wh, no progeny), characterized by a severe fertility defect and affecting expression of a protein (WH) in a family of conserved proteins with multiple WD40 repeats. Knockdown of WH ... [more]

PLoS Biol. Jan. 01, 2016; 14(1);e1002349 [Pubmed: 26751069]

Throughput

  • Low Throughput

Curated By

  • BioGRID