BAIT

OSTM1

1200002H13Rik, HSPC019, gl
osteopetrosis associated transmembrane protein 1
GO Process (1)
GO Function (1)
GO Component (1)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Gene Ontology Cellular Component

Mus musculus
PREY

CCT3

CCT-gamma, CCTG, PIG48, TCP-1-gamma, TRIC5, RP11-443G18.6
chaperonin containing TCP1, subunit 3 (gamma)
GO Process (3)
GO Function (2)
GO Component (6)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking.

Pandruvada SN, Beauregard J, Benjannet S, Pata M, Lazure C, Seidah NG, Vacher J

In humans and in mice, mutations in the Ostm1 gene cause the most severe form of osteopetrosis, a major bone disease, and neuronal degeneration, both of which are associated with early death. To gain insight into Ostm1 function, we first investigated by sequence and biochemical analysis an immature 34-kDa type I transmembrane Ostm1 protein with a unique cytosolic tail. Mature ... [more]

Mol. Cell. Biol. Nov. 23, 2015; 36(3);507-21 [Pubmed: 26598607]

Throughput

  • Low Throughput

Curated By

  • BioGRID