CLCN7
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
KIF5B
Gene Ontology Biological Process
- ATP catabolic process [IBA]
- axon guidance [IBA]
- cytoplasm organization [IMP]
- metabolic process [ISO]
- microtubule-based process [TAS]
- mitochondrial transport [TAS]
- plus-end-directed vesicle transport along microtubule [IMP]
- positive regulation of establishment of protein localization to plasma membrane [ISO]
- positive regulation of potassium ion transport [ISO]
- positive regulation of synaptic transmission, GABAergic [IDA]
- protein localization [IBA]
- regulation of membrane potential [ISO]
- stress granule disassembly [IMP]
- vesicle transport along microtubule [IGI, ISO]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-Western
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner identified by Western blot with a specific polyclonal antibody or second epitope tag. This category is also used if an interacting protein is visualized directly by dye stain or radioactivity. Note that this differs from any co-purification experiment involving affinity capture in that the co-purification experiment involves at least one extra purification step to get rid of potential contaminating proteins.
Publication
Role of Ostm1 Cytosolic Complex with Kinesin 5B in Intracellular Dispersion and Trafficking.
In humans and in mice, mutations in the Ostm1 gene cause the most severe form of osteopetrosis, a major bone disease, and neuronal degeneration, both of which are associated with early death. To gain insight into Ostm1 function, we first investigated by sequence and biochemical analysis an immature 34-kDa type I transmembrane Ostm1 protein with a unique cytosolic tail. Mature ... [more]
Throughput
- Low Throughput
Curated By
- BioGRID