BAIT

USP11

UHX1, RP4-659F15.2
ubiquitin specific peptidase 11
UPS Project
Homo sapiens
PREY

EFHD2

SWS1, RP3-467K16.3
EF-hand domain family, member D2
GO Process (0)
GO Function (0)
GO Component (0)
Homo sapiens

Affinity Capture-MS

An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.

Publication

Regulation of XIAP Turnover Reveals a Role for USP11 in Promotion of Tumorigenesis.

Zhou Z, Luo A, Shrivastava I, He M, Huang Y, Bahar I, Liu Z, Wan Y

The emerging regulatory role of deubiquitinases (DUBs) has been implicated in various fundamental processes and pathogenesis. To determine the pivotal role that DUBs play in mediating tumorigenesis, we have performed a non-biased screen of 67 human DUBs based on a mammary cell transformation assay. This led to the identification of USP11 as a critical determinant of mammary tumor initiation and ... [more]

EBioMedicine Feb. 01, 2017; 15();48-61 [Pubmed: 28040451]

Throughput

  • Low Throughput

Curated By

  • BioGRID