BAIT
KCNE1L
KCNE5, RP1-136J15.2
KCNE1-like
GO Process (15)
GO Function (4)
GO Component (1)
Gene Ontology Biological Process
- atrial cardiac muscle cell action potential [IMP]
- cardiac muscle contraction [IMP]
- membrane repolarization during cardiac muscle cell action potential [IMP]
- negative regulation of potassium ion transmembrane transport [IDA]
- positive regulation of potassium ion transmembrane transport [IDA]
- potassium ion export [IDA]
- potassium ion transmembrane transport [IDA]
- regulation of atrial cardiac muscle cell membrane repolarization [IMP]
- regulation of cation channel activity [IDA]
- regulation of heart contraction [IMP]
- regulation of heart rate by cardiac conduction [IMP]
- regulation of membrane repolarization [IDA]
- regulation of potassium ion transmembrane transport [IDA]
- regulation of ventricular cardiac muscle cell membrane repolarization [IMP]
- ventricular cardiac muscle cell action potential [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
KCNB1
DRK1, EIEE26, KV2.1, h-DRK1
potassium voltage-gated channel, Shab-related subfamily, member 1
GO Process (5)
GO Function (2)
GO Component (2)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
FRET
An interaction is inferred when close proximity of interaction partners is detected by fluorescence resonance energy transfer between pairs of fluorophore-labeled molecules, such as occurs between CFP (donor) and YFP (acceptor) fusion proteins.
Publication
Auxiliary KCNE subunits modulate both homotetrameric Kv2.1 and heterotetrameric Kv2.1/Kv6.4 channels.
The diversity of the voltage-gated K(+) (Kv) channel subfamily Kv2 is increased by interactions with auxiliary β-subunits and by assembly with members of the modulatory so-called silent Kv subfamilies (Kv5-Kv6 and Kv8-Kv9). However, it has not yet been investigated whether these two types of modulating subunits can associate within and modify a single channel complex simultaneously. Here, we demonstrate that ... [more]
Sci Rep Aug. 05, 2015; 5();12813 [Pubmed: 26242757]
Throughput
- Low Throughput
Curated By
- BioGRID