BAIT

ELAVL4

HUD, PNEM
ELAV like neuron-specific RNA binding protein 4
GO Process (2)
GO Function (3)
GO Component (0)

Gene Ontology Biological Process

Gene Ontology Molecular Function

Homo sapiens
PREY

IGF2BP1

AL024068, AW549074, CRD-BP, Crdbp, D030026A21Rik, D11Moh40e, D11Moh45, IMP-1, Neilsen, ZBP-1, Zbp1, RP23-375B1.1
insulin-like growth factor 2 mRNA binding protein 1
Mus musculus

Reconstituted Complex

An interaction is inferred between proteins in vitro. This can include proteins in recombinant form or proteins isolated directly from cells with recombinant or purified bait. For example, GST pull-down assays where a GST-tagged protein is first isolated and then used to fish interactors from cell lysates are considered reconstituted complexes (e.g. PUBMED: 14657240, Fig. 4A or PUBMED: 14761940, Fig. 5). This can also include gel-shifts, surface plasmon resonance, isothermal titration calorimetry (ITC) and bio-layer interferometry (BLI) experiments. The bait-hit directionality may not be clear for 2 interacting proteins. In these cases the directionality is up to the discretion of the curator.

Publication

The insulin-like growth factor mRNA binding-protein IMP-1 and the Ras-regulatory protein G3BP associate with tau mRNA and HuD protein in differentiated P19 neuronal cells.

Atlas R, Behar L, Elliott E, Ginzburg I

Tau mRNA is axonally localized mRNA that is found in developing neurons and targeted by an axonal localization signal (ALS) that is located in the 3'UTR of the message. The tau mRNA is trafficked in an RNA-protein complex (RNP) from the neuronal cell body to the distal parts of the axon, reaching as far as the growth cone. This movement ... [more]

J. Neurochem. May. 01, 2004; 89(3);613-26 [Pubmed: 15086518]

Throughput

  • Low Throughput

Curated By

  • BioGRID