MTMR14
Gene Ontology Biological Process
Gene Ontology Molecular Function
RAB10
Gene Ontology Biological Process
- GTP catabolic process [IBA]
- Golgi to plasma membrane protein transport [ISS]
- Golgi to plasma membrane transport [ISS]
- Rab protein signal transduction [IBA]
- antigen processing and presentation [IMP]
- axonogenesis [ISS]
- basolateral protein localization [ISS]
- cellular response to insulin stimulus [IBA, ISS]
- endoplasmic reticulum tubular network organization [IMP]
- endosomal transport [IMP]
- establishment of neuroblast polarity [ISS]
- establishment of protein localization to endoplasmic reticulum membrane [IMP]
- establishment of protein localization to membrane [IMP]
- intracellular protein transport [IBA]
- membrane organization [TAS]
- polarized epithelial cell differentiation [ISS]
- protein localization to plasma membrane [IBA, ISS]
- protein secretion [IBA]
- regulation of exocytosis [IBA]
- vesicle docking involved in exocytosis [IBA]
- vesicle-mediated transport [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
- Golgi apparatus [IDA]
- cytoplasmic vesicle membrane [TAS]
- endoplasmic reticulum membrane [IDA]
- endoplasmic reticulum tubular network [IDA]
- endosome [IDA]
- endosome membrane [IBA]
- exocyst [ISS]
- extracellular vesicular exosome [IDA]
- focal adhesion [IDA]
- insulin-responsive compartment [IDA]
- plasma membrane [IDA]
- primary cilium [IDA]
- recycling endosome [IDA]
- trans-Golgi network [ISS]
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.
Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated by kinases and phosphatases, two classes of enzymes widely disrupted in human disease. To better understand the functions of the relatively understudied phosphatases, we have used complementary affinity purification and proximity-based interaction proteomics approaches to generate a physical interactome for 140 human proteins harboring phosphatase catalytic domains. We identified 1,335 high-confidence ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
MTMR14 RAB10 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID