BAIT
PTPN23
HD-PTP, HDPTP, PTP-TD14
protein tyrosine phosphatase, non-receptor type 23
GO Process (7)
GO Function (3)
GO Component (7)
Gene Ontology Biological Process
- cilium morphogenesis [IMP]
- negative regulation of epithelial cell migration [IMP]
- peptidyl-tyrosine dephosphorylation [IMP]
- positive regulation of adherens junction organization [IMP]
- positive regulation of early endosome to late endosome transport [IMP]
- positive regulation of homophilic cell adhesion [IMP]
- ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CLINT1
CLINT, ENTH, EPN4, EPNR
clathrin interactor 1
GO Process (2)
GO Function (2)
GO Component (5)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.
Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated by kinases and phosphatases, two classes of enzymes widely disrupted in human disease. To better understand the functions of the relatively understudied phosphatases, we have used complementary affinity purification and proximity-based interaction proteomics approaches to generate a physical interactome for 140 human proteins harboring phosphatase catalytic domains. We identified 1,335 high-confidence ... [more]
Cell Rep Nov. 22, 2016; 17(9);2488-2501 [Pubmed: 27880917]
Throughput
- High Throughput
Curated By
- BioGRID