PTPN4
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
CADM1
Gene Ontology Biological Process
- T cell mediated cytotoxicity [IDA]
- activated T cell proliferation [IDA]
- adherens junction organization [TAS]
- cell junction assembly [TAS]
- cell recognition [IDA, ISS]
- cell-cell junction organization [TAS]
- detection of stimulus [IDA, ISS]
- heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules [ISS]
- homophilic cell adhesion via plasma membrane adhesion molecules [ISS]
- positive regulation of cytokine secretion [IDA]
- positive regulation of natural killer cell mediated cytotoxicity [IDA, ISS]
- susceptibility to natural killer cell mediated cytotoxicity [IDA, ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.
Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated by kinases and phosphatases, two classes of enzymes widely disrupted in human disease. To better understand the functions of the relatively understudied phosphatases, we have used complementary affinity purification and proximity-based interaction proteomics approaches to generate a physical interactome for 140 human proteins harboring phosphatase catalytic domains. We identified 1,335 high-confidence ... [more]
Throughput
- High Throughput
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
PTPN4 CADM1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | - | BioGRID | - |
Curated By
- BioGRID