BAIT
CTDSPL
C3orf8, HYA22, PSR1, RBSP3, SCP3
CTD (carboxy-terminal domain, RNA polymerase II, polypeptide A) small phosphatase-like
GO Process (0)
GO Function (0)
GO Component (1)
Gene Ontology Cellular Component
Homo sapiens
PREY
RFTN1
PIB10, PIG9, RAFTLIN, MIG2
raftlin, lipid raft linker 1
GO Process (11)
GO Function (1)
GO Component (6)
Gene Ontology Biological Process
- B cell receptor signaling pathway [IMP]
- T cell antigen processing and presentation [ISS]
- T cell receptor signaling pathway [ISS]
- dsRNA transport [IMP]
- growth [IMP]
- interleukin-17 production [ISS]
- membrane raft assembly [IMP]
- protein localization to membrane raft [ISS]
- protein transport into membrane raft [ISS]
- response to exogenous dsRNA [IMP]
- toll-like receptor 3 signaling pathway [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Proximity Label-MS
An interaction is inferred when a bait-enzyme fusion protein selectively modifies a vicinal protein with a diffusible reactive product, followed by affinity capture of the modified protein and identification by mass spectrometric methods.
Publication
Phenotypic and Interaction Profiling of the Human Phosphatases Identifies Diverse Mitotic Regulators.
Reversible phosphorylation is a fundamental regulatory mechanism, intricately coordinated by kinases and phosphatases, two classes of enzymes widely disrupted in human disease. To better understand the functions of the relatively understudied phosphatases, we have used complementary affinity purification and proximity-based interaction proteomics approaches to generate a physical interactome for 140 human proteins harboring phosphatase catalytic domains. We identified 1,335 high-confidence ... [more]
Cell Rep Nov. 22, 2016; 17(9);2488-2501 [Pubmed: 27880917]
Throughput
- High Throughput
Additional Notes
- BioID
Curated By
- BioGRID