BAIT
MTMR7
myotubularin related protein 7
GO Process (5)
GO Function (0)
GO Component (1)
Gene Ontology Biological Process
Homo sapiens
PREY
CTBP1
BARS
C-terminal binding protein 1
GO Process (11)
GO Function (7)
GO Component (3)
Gene Ontology Biological Process
- chromatin organization involved in regulation of transcription [IMP]
- negative regulation of cell proliferation [TAS]
- negative regulation of histone H4 acetylation [IMP]
- negative regulation of histone acetylation [IMP]
- negative regulation of transcription from RNA polymerase II promoter [IMP]
- negative regulation of transcription, DNA-templated [ISS]
- positive regulation of histone deacetylation [IMP]
- protein phosphorylation [TAS]
- regulation of cell cycle [IMP]
- viral genome replication [TAS]
- white fat cell differentiation [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Defining the Protein-Protein Interaction Network of the Human Protein Tyrosine Phosphatase Family.
Protein tyrosine phosphorylation, which plays a vital role in a variety of human cellular processes, is coordinated by protein tyrosine kinases and protein tyrosine phosphatases (PTPs). Genomic studies provide compelling evidence that PTPs are frequently mutated in various human cancers, suggesting that they have important roles in tumor suppression. However, the cellular functions and regulatory machineries of most PTPs are ... [more]
Mol. Cell Proteomics Sep. 01, 2016; 15(9);3030-44 [Pubmed: 27432908]
Throughput
- High Throughput
Additional Notes
- high-confidence candidate interacting protein
Curated By
- BioGRID