ERP44
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
ZFPM1
Gene Ontology Biological Process
- T-helper cell lineage commitment [IC]
- atrial septum morphogenesis [ISS]
- atrioventricular valve morphogenesis [ISS]
- blood coagulation [TAS]
- cardiac muscle tissue morphogenesis [ISS]
- embryonic hemopoiesis [ISS]
- erythrocyte differentiation [ISS]
- heart development [IBA]
- megakaryocyte differentiation [IBA, ISS]
- mitral valve formation [ISS]
- negative regulation of fat cell differentiation [ISS]
- negative regulation of interleukin-4 biosynthetic process [IDA]
- negative regulation of mast cell differentiation [ISS]
- negative regulation of protein binding [ISS]
- negative regulation of transcription from RNA polymerase II promoter [IDA]
- outflow tract morphogenesis [ISS]
- platelet formation [IGI]
- positive regulation of interferon-gamma biosynthetic process [IDA]
- regulation of definitive erythrocyte differentiation [IDA, IMP]
- transcriptional activation by promoter-enhancer looping [ISS]
- tricuspid valve formation [ISS]
- ventricular septum morphogenesis [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999999982 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999999982, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| ERP44 ZFPM1 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3033334 |
Curated By
- BioGRID