CHRNB3
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TYRO3
Gene Ontology Biological Process
- apoptotic cell clearance [ISS]
- cell adhesion [NAS]
- forebrain cell migration [ISS]
- negative regulation of inflammatory response [ISS]
- negative regulation of innate immune response [ISS]
- negative regulation of neuron apoptotic process [ISS]
- negative regulation of toll-like receptor signaling pathway [ISS]
- neuron cellular homeostasis [ISS]
- ovulation cycle [ISS]
- peptidyl-tyrosine phosphorylation [IDA, NAS]
- phosphatidylinositol 3-kinase signaling [NAS]
- platelet activation [ISS]
- platelet aggregation [ISS]
- protein autophosphorylation [IDA]
- protein kinase B signaling [ISS]
- secretion by cell [ISS]
- signal transduction [NAS]
- signal transduction by phosphorylation [NAS]
- spermatogenesis [ISS]
- substrate adhesion-dependent cell spreading [ISS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999999978 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999999978, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
---|---|---|---|---|---|---|
CHRNB3 TYRO3 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 1192479 | |
CHRNB3 TYRO3 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3047464 |
Curated By
- BioGRID