CAMK2D
Gene Ontology Biological Process
- cardiac muscle cell contraction [ISS]
- cellular response to calcium ion [TAS]
- cytokine-mediated signaling pathway [TAS]
- endoplasmic reticulum calcium ion homeostasis [ISS]
- interferon-gamma-mediated signaling pathway [TAS]
- negative regulation of sodium ion transmembrane transport [IDA]
- negative regulation of sodium ion transmembrane transporter activity [IDA]
- peptidyl-serine phosphorylation [IDA]
- peptidyl-threonine phosphorylation [IDA]
- positive regulation of cardiac muscle hypertrophy [IMP]
- protein autophosphorylation [IDA]
- protein oligomerization [IDA]
- protein phosphorylation [IDA]
- regulation of cardiac muscle cell action potential [ISS]
- regulation of cardiac muscle cell action potential involved in regulation of contraction [IC]
- regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion [IC, TAS]
- regulation of cell communication by electrical coupling [ISS]
- regulation of cell communication by electrical coupling involved in cardiac conduction [IC]
- regulation of cell growth [NAS]
- regulation of cellular localization [IMP]
- regulation of generation of L-type calcium current [ISS]
- regulation of heart contraction [TAS]
- regulation of heart rate by cardiac conduction [IC]
- regulation of histone deacetylase activity [TAS]
- regulation of membrane depolarization [IDA]
- regulation of relaxation of cardiac muscle [IDA]
- regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum [ISS]
- regulation of ryanodine-sensitive calcium-release channel activity [TAS]
- regulation of the force of heart contraction [TAS]
- regulation of transcription from RNA polymerase II promoter [TAS]
- relaxation of cardiac muscle [ISS]
- synaptic transmission [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
UNG
Gene Ontology Biological Process
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999989577 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999989577, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| CAMK2D UNG | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3054801 |
Curated By
- BioGRID