BLVRA
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
TBX20
Gene Ontology Biological Process
- aortic valve morphogenesis [IMP]
- atrial septum morphogenesis [IMP]
- cardiac chamber formation [ISS]
- cardiac muscle tissue morphogenesis [ISS]
- cardiac right ventricle morphogenesis [ISS]
- cardiac septum development [ISS]
- dorsal/ventral pattern formation [ISS]
- embryonic heart tube morphogenesis [ISS]
- endocardial cushion formation [ISS]
- endocardial cushion morphogenesis [ISS]
- endoderm formation [ISS]
- foramen ovale closure [IMP]
- heart looping [ISS]
- lateral mesoderm formation [ISS]
- negative regulation of transcription from RNA polymerase II promoter [ISS]
- negative regulation of transcription, DNA-templated [ISS]
- outflow tract septum morphogenesis [IMP]
- pericardium morphogenesis [ISS]
- positive regulation of cardiac muscle cell proliferation [ISS]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- pulmonary valve formation [ISS]
- pulmonary vein morphogenesis [IMP]
- tricuspid valve development [ISS]
- visceral motor neuron differentiation [ISS]
Gene Ontology Molecular Function
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.999897779 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.999897779, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| BLVRA TBX20 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.997 | BioGRID | 1181497 | |
| BLVRA TBX20 | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 1 | BioGRID | 3063518 |
Curated By
- BioGRID