BAIT
WNT7A
wingless-type MMTV integration site family, member 7A
GO Process (22)
GO Function (4)
GO Component (5)
Gene Ontology Biological Process
- Wnt signaling pathway involved in wound healing, spreading of epidermal cells [IDA]
- canonical Wnt signaling pathway [IDA]
- cartilage condensation [IDA]
- cell fate commitment [IBA]
- cell proliferation in forebrain [IDA]
- cellular response to transforming growth factor beta stimulus [IEP]
- chondrocyte differentiation [IDA]
- embryonic axis specification [IMP]
- embryonic digit morphogenesis [IMP]
- embryonic forelimb morphogenesis [IMP]
- embryonic hindlimb morphogenesis [IMP]
- lens fiber cell development [ISS]
- negative regulation of neurogenesis [IDA]
- neuron differentiation [IBA]
- palate development [IMP]
- positive regulation of JNK cascade [IBA]
- positive regulation of epithelial cell proliferation involved in wound healing [IDA]
- positive regulation of synapse assembly [IDA]
- positive regulation of transcription from RNA polymerase II promoter [IDA]
- positive regulation of transcription, DNA-templated [IDA]
- sex differentiation [TAS]
- stem cell development [IDA]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
FSTL1
FRP, FSL1, MIR198
follistatin-like 1
GO Process (1)
GO Function (1)
GO Component (3)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Nature May. 25, 2017; 545(7655);505-509 [Pubmed: 28514442]
Quantitative Score
- 0.85998345 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.85998345, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Curated By
- BioGRID