BSG
Gene Ontology Biological Process
- blood coagulation [TAS]
- cell surface receptor signaling pathway [TAS]
- cellular metabolic process [TAS]
- extracellular matrix disassembly [TAS]
- extracellular matrix organization [TAS]
- leukocyte migration [TAS]
- protein targeting to plasma membrane [ISS]
- pyruvate metabolic process [TAS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
GPD1L
Gene Ontology Biological Process
- NAD metabolic process [IMP]
- cellular lipid metabolic process [TAS]
- glycerophospholipid biosynthetic process [TAS]
- negative regulation of peptidyl-serine phosphorylation [IMP]
- negative regulation of protein kinase C signaling [IMP]
- phosphatidic acid biosynthetic process [TAS]
- phospholipid metabolic process [TAS]
- positive regulation of protein localization to cell surface [IMP]
- positive regulation of sodium ion transport [IMP]
- regulation of heart rate [IMP]
- regulation of sodium ion transmembrane transporter activity [IMP]
- regulation of ventricular cardiac muscle cell membrane depolarization [IMP]
- small molecule metabolic process [TAS]
- triglyceride biosynthetic process [TAS]
- ventricular cardiac muscle cell action potential [IMP]
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Quantitative Score
- 0.8219425 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.8219425, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Related interactions
| Interaction | Experimental Evidence Code | Dataset | Throughput | Score | Curated By | Notes |
|---|---|---|---|---|---|---|
| BSG GPD1L | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.9483 | BioGRID | 1178725 | |
| BSG GPD1L | Affinity Capture-MS Affinity Capture-MS An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods. | High | 0.8732 | BioGRID | 3127911 |
Curated By
- BioGRID