BAIT
SLC38A7
SNAT7
solute carrier family 38, member 7
GO Process (14)
GO Function (10)
GO Component (2)
Gene Ontology Biological Process
- L-alanine transport [IBA]
- L-aspartate transmembrane transport [IBA]
- L-glutamate transmembrane transport [IBA]
- L-glutamate transport [IBA]
- L-histidine transmembrane transport [IBA]
- L-serine transport [IBA]
- amino acid transmembrane transport [IBA]
- asparagine transport [IBA]
- aspartate transport [IBA]
- cation transmembrane transport [IBA]
- glutamine transport [IBA]
- histidine transport [IBA]
- methionine transport [IBA]
- sodium ion transport [ISS]
Gene Ontology Molecular Function- L-alanine transmembrane transporter activity [IBA]
- L-amino acid transmembrane transporter activity [ISS]
- L-asparagine transmembrane transporter activity [IBA]
- L-aspartate transmembrane transporter activity [IBA]
- L-glutamate transmembrane transporter activity [IBA]
- L-glutamine transmembrane transporter activity [IBA, ISS]
- L-histidine transmembrane transporter activity [IBA]
- L-leucine transmembrane transporter activity [IBA]
- L-methionine transmembrane transporter activity [IBA]
- L-serine transmembrane transporter activity [IBA]
- L-alanine transmembrane transporter activity [IBA]
- L-amino acid transmembrane transporter activity [ISS]
- L-asparagine transmembrane transporter activity [IBA]
- L-aspartate transmembrane transporter activity [IBA]
- L-glutamate transmembrane transporter activity [IBA]
- L-glutamine transmembrane transporter activity [IBA, ISS]
- L-histidine transmembrane transporter activity [IBA]
- L-leucine transmembrane transporter activity [IBA]
- L-methionine transmembrane transporter activity [IBA]
- L-serine transmembrane transporter activity [IBA]
Gene Ontology Cellular Component
Homo sapiens
PREY
ACTL6B
ACTL6, BAF53B
actin-like 6B
GO Process (3)
GO Function (2)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Nature May. 25, 2017; 545(7655);505-509 [Pubmed: 28514442]
Quantitative Score
- 0.790743617 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.790743617, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Curated By
- BioGRID