BAIT
ATP6V1G1
ATP6G, ATP6G1, ATP6GL, ATP6J, Vma10, RP11-402G3.1
ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G1
GO Process (6)
GO Function (1)
GO Component (4)
Gene Ontology Biological Process
Gene Ontology Molecular Function
Gene Ontology Cellular Component
Homo sapiens
PREY
CARM1
PRMT4
coactivator-associated arginine methyltransferase 1
GO Process (9)
GO Function (12)
GO Component (4)
Gene Ontology Biological Process
- cellular lipid metabolic process [TAS]
- histone H3-R17 methylation [ISS]
- histone H3-R2 methylation [IMP]
- histone methylation [IDA, ISS]
- peptidyl-arginine methylation, to asymmetrical-dimethyl arginine [IBA]
- positive regulation of fat cell differentiation [ISS]
- regulation of intracellular estrogen receptor signaling pathway [ISS]
- regulation of transcription, DNA-templated [IBA, ISS]
- small molecule metabolic process [TAS]
Gene Ontology Molecular Function- beta-catenin binding [TAS]
- histone methyltransferase activity [IDA]
- histone methyltransferase activity (H3-R17 specific) [ISS]
- histone-arginine N-methyltransferase activity [IBA]
- ligand-dependent nuclear receptor transcription coactivator activity [ISS]
- lysine-acetylated histone binding [ISS]
- protein binding [IPI]
- protein methyltransferase activity [ISS]
- protein-arginine N-methyltransferase activity [ISS]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA, ISS]
- transcription coactivator activity [ISS]
- transcription regulatory region DNA binding [ISS]
- beta-catenin binding [TAS]
- histone methyltransferase activity [IDA]
- histone methyltransferase activity (H3-R17 specific) [ISS]
- histone-arginine N-methyltransferase activity [IBA]
- ligand-dependent nuclear receptor transcription coactivator activity [ISS]
- lysine-acetylated histone binding [ISS]
- protein binding [IPI]
- protein methyltransferase activity [ISS]
- protein-arginine N-methyltransferase activity [ISS]
- protein-arginine omega-N asymmetric methyltransferase activity [IBA, ISS]
- transcription coactivator activity [ISS]
- transcription regulatory region DNA binding [ISS]
Homo sapiens
Affinity Capture-MS
An interaction is inferred when a bait protein is affinity captured from cell extracts by either polyclonal antibody or epitope tag and the associated interaction partner is identified by mass spectrometric methods.
Publication
Architecture of the human interactome defines protein communities and disease networks.
The physiology of a cell can be viewed as the product of thousands of proteins acting in concert to shape the cellular response. Coordination is achieved in part through networks of protein-protein interactions that assemble functionally related proteins into complexes, organelles, and signal transduction pathways. Understanding the architecture of the human proteome has the potential to inform cellular, structural, and ... [more]
Nature May. 25, 2017; 545(7655);505-509 [Pubmed: 28514442]
Quantitative Score
- 0.758149038 [compPASS Score]
Throughput
- High Throughput
Additional Notes
- BioPlex 2.0 HEK 293T cells CompPASS score = 0.758149038, threshold = 0.75. Quantitative scores calculated by CompPASS-Plus (Huttlin et al. Cell, 2015, PMID: 26186194).
- See BioPlex Interactome for details (https://bioplex.hms.harvard.edu/index.php).
- This data has also been reanalyzed as part of BioPlex 3.0 (PMID: 33961781) and may be re-scored from BioPlex 1.0 (PMID: 26186194). Only scores from within BioPlex 2.0 (PMID: 28514442) should be compared directly.
Curated By
- BioGRID