Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.

Publication

mBET3 is required for the organization of the TRAPP complexes.

Menon S, Cai H, Lu H, Dong G, Cai Y, Reinisch K, Ferro-Novick S

Large tethering complexes mediate the initial interaction of a transport vesicle with its target membrane. There are two forms of the multi-subunit tethering complex called TRAPP (TRAPPI and TRAPPII) that tether transport vesicles in different trafficking steps. Understanding TRAPP complex assembly and the protein-protein interactions among the subunits is an important step in elucidating the function of this tether. Here ... [more]

Biochem. Biophys. Res. Commun. Nov. 24, 2006; 350(3);669-77 [Pubmed: 17027922]

Throughput

Low Throughput

Related interactions

Interaction	Experimental Evidence Code	Dataset	Throughput	Score	Curated By	Notes
TRAPPC1 TRAPPC4	Co-fractionation Co-fractionation Interaction inferred from the presence of two or more protein subunits in a partially purified protein preparation. If co-fractionation is demonstrated between 3 or more proteins, then add them as a complex.	Pourhaghighi R (2020)	High	0.988	BioGRID	2676264

Curated By

BioGRID

Interaction Summary

TRAPPC4

Gene Ontology Biological Process

Gene Ontology Molecular Function

Rab guanyl-nucleotide exchange factor activity [IBA]protein binding [IPI]

Gene Ontology Cellular Component

TRAPPC1